Type 2 diabetes drugs may lead to cardiovascular diseases, new study suggests


The research suggests that doctors should prefer prescribing newer classes of anti diabetic medicines over the older ones.

If you suffer from Type 2 diabetes, you may be prone to cardiovascular health issues too.

Yes, you read that right. If a new study is to be believed, consuming two commonly used drugs for the treatment of Type 2 diabetes can cause cardiovascular events such as heart attack, stroke, amputation and heart failure. These drugs are Sulfonylureas and basal insulin.

According to the study which has been published in the journal JAMA Network Open, patients who consume one of the above-mentioned drugs are more likely to experience cardiovascular issues than those people who consume DD4 inhibitors, a newer class of drugs used for diabetic patients.

“People should know if the medications they are taking to treat their diabetes could lead to serious cardiovascular harm. This calls for a paradigm shift in the treatment of Type 2 diabetes,” news agency IANS quoted lead author Matthew O’Brien, Assistant Professor from the Northwestern University in the US, as saying.

The research suggests that doctors should prefer prescribing newer classes of anti diabetic medicines over the older ones.

The new medicines include GLP-1 agonists (Liraglutide), SGLT-2 inhibitors (Empagliflozin)or DPP-4 inhibitors (Sitagliptin). Physicians should give these medicines more routinely after Metformin, rather than Sulfonylureas or basal insulin.

One of the common reasons why doctors don’t prescribe these medicines very often is the expensive pricing of these drugs. They are much more expensive than Sulfonylureas.

According to the research team, their study should come as an eye-opener for physicians and should force them to think about the risks they pose in terms of cardiovascular diseases.

The researchers suggest that doctors should shift their prescribing patterns and move to newer drugs that have more favorable cardiovascular profiles.

To conduct the study, the research team observed data received from 132,737 patients with Type-2 diabetes who were starting second-line treatment.

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